apalutamide will minimize the extent or impact of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP3A4 inducer, with medication that are CYP3A4 substrates may result in lessen publicity to those remedies.posaconazole will boost the stage or result of

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